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KMID : 0604520100360030207
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Journal of the Society of Cosmetic Scientists of Korea
2010 Volume.36 No. 3 p.207 ~ p.213
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Skin Whitening Effects of Caragana sinica Rehder Extract Fermented by Saccharomyces cerevisiae KCTC 7913
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Seok Ji-Hyun
Lee Sun-Young
Chae Eun-Jung
Choi Shin-Wook
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Abstract
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In this study, we evaluated antioxidative effects and skin whitening effects of extract of Caragana sinica fermented by S. cerevisiae KCTC 7913. At first, Caragana sinica was fermented via inoculation of Saccharomyces cerevisiae KCTC 7913 and then extracted for fermented C. sinica. It has shown that more increased of melanogenesis inhibition activity in a dose-dependent manner on B16F10 melanoma cells and elevated the amount of resveratrol contents by HPLC analysis than non-fermented. Furthermore, the extract of fermented C. sinica was inhibitory effects against tyrosinase, a key enzyme of melanogenesis pathway, more than non-fermented C. sinica extract. And it did not show the skin irritation. Therefore, fermented C. sinica extracts might be used as safe cosmetic ingredients.
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KEYWORD
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fermentation, whitening, antioxidant, Caragana sinica Rehder, resveratrol
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